北京沙东生物技术有限公司的MCAO线栓业务已经移交给北京西浓科技有限公司接管，西浓科技公司成立于2014年，注册于北京市中关村高科技园区，专注于各种实验动物的脑缺血模型的技术开发、技术咨询和相关产品的生产、销售，致力于为广大客户提供优质的与MCAO模型相关的一站式服务。创始人具有雄厚的猴、狗、兔、大鼠、小鼠等实验动物的模型制备技术，其中对大鼠/小鼠的大脑中动脉线栓模型（MCAO模型）具有20多年的制备经验，独家研发的主要产品MCAO模型线栓已上市销售十多年，已被美国、加拿大、香港、中国大陆等的科研机构、大学、医院广泛采用，研究论文发表于国内外数十种优秀专业期刊(见附录)。MCAO线栓业务以前由北京沙东生物技术有限公司经营，从2014年开始将由西浓科技独立接管经营与MCAO业务相关的研发、生产、销售及售后服务，之前的联系电话、邮箱等不变，并启用全国统一的服务热线400-863-6007,公司官网为www.mcao-model.com.cn。
附录：使用MCAO栓线产品最近发表的部分论文 （论文中的“Beijing Sunbio Biotech Co. Ltd.”既是西浓科技的前身）
1. Luo Y, Yang YP, Li WH, et al. Neuroprotective effects of madecassoside against focal cerebral ischemia reperfusion injury in rats. Brain Research. Available online 13 April 2014.
2. Wang ZX, Huang WQ, Zuo ZY. Perioperative aspirin improves neurological outcome after focal brain ischemia possibly via inhibition of Notch 1 in rat. Journal of Neuroinflammation 2014, 11:56.
3. Sun L, Qiang R, Yang Y, et al. L-Serine Treatment May Improve Neurorestoration of Rats after Permanent Focal Cerebral Ischemia Potentially Through Improvement of Neurorepair. PLoS ONE 2014, 9(3): e93405. doi: 10.1371/journal.pone.009340.
4. Lin Y, Zhang JC, Fu J, et al. Hyperforin attenuates brain damage induced by transient middle cerebral artery occlusion (MCAO) in rats via inhibition of TRPC6 channels degradation. Journal of Cerebral Blood Flow & Metabolism (2013) 33, 253–262;
5. An S, Kuang YY, Shen T, et al. Brain-targeting delivery for RNAi neuroprotection against cerebral ischemia reperfusion injury. Biomaterials 34 (2013) 8949-8959.
6. Fu J, Xue R, Gu JF, et al. Neuroprotective effect of calcitriol on ischemic/reperfusion injury through the NR3A/CREB pathways in the rat hippocampus. Molecular Medicine Reports. 2013, 1708-1714.
7. Cheng FF, Lu Y, Zhong XG. Baicalin''''''''''''''''''''''''''''''''''''''''''''''''''''''''''''''''s Therapeutic Time Window of Neuroprotection during Transient Focal Cerebral Ischemia and Its Antioxidative Effects In Vitro and In Vivo. Evidence-Based Complementary and Alternative Medicine, vol.2013, PP.1-11, 2013.
8. Chen XY, Sun XC, Su HX. Upregulation of myeloid cell leukemia-1 potentially modulates beclin-1-dependent autophagy in ischemic stroke in rats. BMC Neuroscience, 2013, 14:56.
9. Dong BB, Cai M, Fang ZP. Hemopexin induces neuroprotection in the rat subjected to focal cerebral ischemia. BMC Neuroscience 2013, 14:58.
10. Lan R, Xiang J, Zhang Y. PI3K/Akt Pathway Contributes to Neurovascular Unit Protection of Xiao-Xu-Ming Decoction against Focal Cerebral Ischemia and Reperfusion Injury in Rats. Evidence-Based Complementary and Alternative Medicine, Volume 2013.
11. Li JJ, Sheng WL, Feng CZ. Pyrrolidine dithiocarbamate attenuates brain Aβ increase and improves long-term neurological outcome in rats after transient focal brain ischemia. Neurobiol Dis. 2012; 45(1): 564–572.
12. Guo JY, Ding J, Yuan F. Dose-Dependent Protective Effect of Bisperoxovanadium against Acute Cerebral Ischemia in a Rat Model of Ischemia/Reperfusion Injury. Int. J. Mol. Sci. 2013, 14, 12013-12022.
13. Li LL, Zuo ZY. Isoflurane postconditioning induces neuroprotection via Akt activation and attenuation of increased mitochondrial membrane permeability. Neuroscience. 2011 December 29; 199: 44–50.
14. Li H, Yin JB, Li LL, et al. Isoflurance postconditioning reduces ischemia-induced nuclear factor-kB activation and interleukin 1β production to provide neuroprotection in rats and mice. Neurobiology of Disease. Available online 8 January 2013.
15. Zhu SP, Li Y, Lu HY, et al. Imaging the Early Cerebral Blood Flow Changes in Rat Middle Cerebral Artery Occlusion Stroke Model. 34th Annual International Conference of the IEEE EMBS San Diego, California USA, 28 August - 1 September, 2012.
16. Cheng FF, Zhong XG, Lu Y, et al. Refined Qingkailing ProtectsMCAOMice from Endoplasmic Reticulum Stress-Induced Apoptosis with a Broad Time Window. Evidence-Based Complementary and Alternative Medicine. 2012, Article ID 567872, 12 pages.
17. Zhai FG, Zhang XP, Guan Y, et al. Expression profiles of microRNAs after focal cerebral ischemia/reperfusion injury in rats. Neural Regen Res. 2012; 7(12):917-923.
18. Li LL, Zuo ZY. Glutamate transporter type 3 knockout reduces brain tolerance to focal brain ischemia in mice. Journal of Cerebral Blood Flow & Metabolism . 2011; 31:1283-1292.
19. Ding H, Yan C-Z, Shi H, Zhao Y-S, Chang S-Y, et al. Hepcidin Is Involved in Iron Regulation in the Ischemic Brain. PLoS ONE.2011, 6(9): e25324.
20. Han QQ, Li B, Feng H, et al. The promotion of cerebral ischemia recovery in rats by laminin-binding BDNF. Biomaterials. 2011; 32(22):5077-5085.
21. Xu HY, Zhang CW, Zhang CX. Effect of propofol pretreatment on apoptosis in rat brain cortex after focal cerebral ischemia and reperfusion. Neural Regen Res. 2011;6(14):1086-1090.
22. Liu K, Li Z, Wu T, et al. Role of Rho Kinase in Microvascular Damage Following Cerebral Ischemia Reperfusion in Rats. Int. J. Mol. Sci. 2011; 12: 1222-1231.
23. Yang L, Zhang BS, Yin L, et al. Tanshinone IIA Prevented Brain Iron Dyshomeostasis in Cerebral Ischemic Rats. Cell Physiol Biochem, 2011; 27:23-30.
24. Sun L, Ai J, Wang N, et al. Cerebral Ischemia Elicits Aberration in Myocardium Contractile Function and Intracellular Calcium Handling. Cell Physiol Biochem 2010; 26:421-430.
25. Zhang F, Wu Y, Jia J et al. Pre-Ischemic Treadmill Training Induces Tolerance to Brain Ischemia: Involvement of Glutamate and ERK1/2. Molecules. 2010；15： 5246-5257.
26. Wu Y, Ye XH, Guo PP, et al. Neuroprotective Effect of Lipoxin A4 Methy Ester in a Rat Model of Permanent Focal Cerebral Ischemia. J Mol Neurosci. 2010; 22:226-234.
27. Li LL, Zuo ZY. Isoflurane preconditioning improves short-term and long-term neurological outcome after focal brain ischemia in adult rats. J Neuroscience.2009; 164:497-506.
28. Xing BZ, Chen H, Zhang M. PhD. Ischemic Postconditioning Inhibits Apoptosis after Focal Cerebral Ischemia/Reperfusion Injury in the Rat. Stroke. 2008; 39:2362-2369.
29. Xing BZ, Chen H, Zhang M, et al. Ischemic post-conditioning protects brain and reduces inflammation in a rat model of focal cerebral ischemia/reperfusion. Journal of Neurochemistry. 2008; 105(5):1737-1745.